It has been shown that high resolution HLA typing (HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DQB1 and HLA-DPB1) may be relevant in transplantation to identify a full match, even when the donor is related.
Human Leukocyte Antigen (HLA) antibodies are specialized components of the immune system designed to recognize and neutralize foreign substances. These antibodies specifically target Human Leukocyte Antigens, which are proteins found on the surface of almost all nucleated cells throughout the body. Understanding these antibodies is important because they represent the body’s immunological ...
Human leukocyte antigen (HLA) are proteins found on most cells in the body. HLA are used by doctors to help match blood stem cell donors with patients.
The human major histocompatibility complex HLA is located on the short arm of chromosome 6. It is known to be the most polymorphic genetic system in humans. The biological role of the HLA class I and class II molecules is to present processed ...
The human leukocyte antigen (HLA) system (the major histocompatibility complex [MHC] in humans) is an important part of the immune system and is controlled by genes located on chromosome 6.
Human leukocyte antigen (HLA), any of numerous antigens involved in the major histocompatibility complex (MHC) in humans. The HLA genes, of which more than 200 are known, encode the cell-surface proteins of the MHC. Variability in HLA genes serves a critical role in adaptive immunity.
The HLA is a group of genes within human DNA that makes special proteins called human leukocyte antigens (HLA). They are present on the surface of various cells throughout the body.
This test checks your blood for antibodies against a cell marker called a human leukocyte antigen (HLA). The test is done if you need an organ transplant, to help find a donor organ that will work in your body.
The human leukocyte antigen (HLA) system is one of the most crucial host factors influencing disease progression in bacterial and viral infections. This review provides the basic concepts of the structure and function of HLA molecules in humans. ...
Donor-specific antibodies against mismatched HLA proteins cause allograft failure, but the structural epitopes recognized by these antibodies are not well defined. Killian et al. identify immunodominant HLA-A∗01:01 epitopes that are localized specifically on the HLA crown and conserved across transplant recipients. These findings provide a framework for understanding the immunogenicity of ...
The human leukocyte antigen (HLA) system (the major histocompatibility complex [MHC] in humans) is an important part of the immune system and is controlled by genes located on chromosome 6.