Figure 1: Myosin and its structural changes in its cyclic interactions with actin. The pivotal question is, what is the molecular mechanism behind actin activation of myosin that determines the force ...
Myosin in muscles behaves in a unique way, which might explain why muscles have such strong contractile power. A cartoon showing the asymmetry in the weak binding between myosin and actin that biases ...
Actomyosin is a protein complex composed of actin and myosin. It is found in muscle fibers where it plays a role in muscle contraction. Actin is one of the most abundant proteins in eukaryotes. It ...
Mutations in β-cardiac myosin, the predominant motor protein for human heart contraction, can alter power output and cause cardiomyopathy. However, measurements of the intrinsic force, velocity, and ...
Setting out to identify all proteins that make up the sarcomere, the basic contractile unit of muscle cells, resulted in an unexpected revelation, providing experimental evidence that helps explain a ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 24 (Jun. 15, 2004), pp. 8930-8935 (6 pages) Structural studies of myosin have induced some of the ...
Cells use the polymerization of actin alone to create some types of movement, but many other forms of movement require interplay between actin and an enzyme called ...
The Fowler laboratory studies cellular architecture: how cells spatially organize themselves and their interior compartments to achieve intricate geometries, mechanical strength, and physiological ...
Over 80,000 years ago, Homo sapiens started leaving their African homeland to colonize the world. This great migration first brought them to far east Asia then, around 42,000 years ago, to Europe.
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