Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

Scientists first observed the biological phenomenon of restriction and modification in the 1950s, but they did not identify and isolate restriction enzymes until the late 1960s. 3 In 1970, Hamilton ...

EcoR124I is a type I DNA restriction and modification enzyme. The single-molecule magnetic tweezers technique reveals that this sophisticated molecular machine is capable of moving thousands of base ...

BOSTON – A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. The recent ...

Lead author Kathleen A. Christie, PhD, postdoctoral researcher at Harvard Medical School; research fellow at Massachusetts General Hospital. If you’ve ever spent time in a molecular biology lab, there ...

Phylogenetic relationships and evolutionary patterns within the arachnid order Solifugae are poorly understood and largely unresolved due to conserved morphology and scarce genomic resources. In this ...

DUBLIN--(BUSINESS WIRE)--The "Global Restriction Endonuclease Market By Type (I, II, III, IV), By Application (Genetic Engineering, DNA Mapping, Gene Sequencing and Others), By End Type, By Source, By ...

A team led by investigators has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. A team led by investigators at Massachusetts General Hospital (MGH ...

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. The recent innovation, ...