Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies ...

Our lab studies the mechanism of eukaryotic chromosome replication. Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental ...

In mitosis, DNA replication is initiated through the actions of various multiprotein complexes that recognize the start sites within a chromosome and cause the separation of DNA into two ...

The replication of DNA is initiated at particular sites on the genome called replication origins (ROs). Understanding the constraints that regulate the distribution of ROs across different organisms ...

A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals ...

Summary To successfully colonize their host, pathogens produce effectors that can interfere with host cellular processes. Here we investigated the function of CRN13 candidate effectors produced by ...