Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory conditions. A critical factor, however, is whether the active substances actually ...

Researchers have revealed how polymyxins, crucial last-resort antibiotics, break down bacterial armor by forcing cells to overproduce and shed it. Astonishingly, the drugs only kill bacteria when they ...

Probiotics can support gut health during antibiotics, but they don’t work the same for everyone.

The confluence of events that have engulfed the discovery, clinical development, and the market for antibiotics over the last two decades is evolving. And not for the better. When I first wrote ...