Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the ...
New Computational Model Matches Drugs to Protein Synthesis Disruptors in Hereditary Diseases, Cancer
Genetic diseases that result from truncated proteins can be targeted by so-called nonsense suppression therapies—drugs that prevent protein translation from terminating prematurely. A new ...
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Federal Grants Support Research on AI-driven Protein Design
Two projects at the University of California, Davis, that use artificial intelligence to design and engineer proteins for ...
Researchers showed that many mitochondrial proteins enter the organelle during synthesis, guided by folding patterns and structural signals. This discovery revises decades of biochemical models. Mitoc ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
Researchers at the Max Planck Institute for Brain Research have mapped the molecular landscape of the mouse hippocampus, a ...
This is a preview. Log in through your library . Abstract Protein synthesis and degradation are essential processes that regulate cell status. Because labeling in bulky organs, such as fruits, is ...
A study on how aging impacts the brain in killifish has found that getting old selectively impairs the production of some key DNA- and RNA-binding proteins. And this change contributes to hallmarks of ...
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