Researchers identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.

ALS is a progressive disease, meaning it worsens over time. Although there is no cure for ALS, medications and therapies are available to help manage the symptoms, slow the disease course, and prolong ...

An experimental drug has successfully slowed the progress of amyotrophic lateral sclerosis in a phase 2 study, its developer announced on Tuesday. Participants taking AMX0035, designed to reduce ...

Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a progressive neurodegenerative disease. It affects your nerves and muscle tissue and worsens over time, eventually becoming fatal.

For columnist Dagmar Munn, reducing uncertainty in one area of her life with ALS would mean keeping her ALS progression right where it is.

People with end stage ALS lose the ability to breathe, have limited mobility as muscles become paralyzed, and may no longer be able to speak. Amyotrophic lateral sclerosis (ALS) affects certain nerve ...

Recent research from Houston Methodist Hospital showed that a new immunotherapy was safe for patients with ALS and also revealed surprising results that could bring hope to patients who have this ...

Approximately 5,000 people in the U.S. develop amyotrophic lateral sclerosis (ALS) each year. On average, they survive for only two to five years after being diagnosed, according to the Centers for ...

Pictured are nuclei of induced pluripotent stem cell (iPSC)-derived motor neurons stained for contrast. The nucleus on the left has been treated with DMSO (control) and appears mostly blue. The ...