NFL Week 5 odds, picks, predictions, TV channel, streaming information for Thursday Night Football game between San Francisco ...

The 49ers will re-evaluate Brock Purdy’s sore toe from Sunday’s loss to the Jaguars and with a Thursday game fast approaching ...

There were plenty of glaring issues to choose from throughout the 49ers’ woeful performance against the Jaguars on Sunday, ...

The 49ers never did sack Jacksonville quarterback Trevor Lawrence, whose jersey was kept clean while going 21-for-31 for 174 ...

The NFL has made a major schedule change, flexing the 49ers-Buccaneers into a late slot and pushing down Patriots-Saints.

The San Francisco 49ers ran into an old friend on Sunday. Jacksonville Jaguars defensive lineman Arik Armstead had a 'special ...

San Francisco 49ers QB Brock Purdy woke up Monday with "real soreness" in his injured toe after playing in Sunday's loss to ...

San Francisco 49ers defensive coordinator Robert Saleh and Jacksonville Jaguars head coach Liam Coen had to be separated ...

Devin Lloyd continued his heater of a month with a dominant game against the 49ers. The fourth-year linebacker was all over ...

The formula for success on offense for the San Francisco 49ers has been pretty consistent since Kyle Shanahan took over as ...

49ers receiver Ricky Pearsall is now questionable to return with a knee injury. The San Francisco 49ers cannot seem to shake ...

Brock Purdy will return to the starting lineup on Sunday in Week 4 against the Jacksonville Jaguars after missing the last ...