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This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

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An inherent principle of publication is that others should be able to replicate and build upon the authors' published claims. A condition of publication in a Nature Portfolio journal is that authors ...

Various types of mammalian extracellular glycan are produced in the secretory pathway. This Review covers the enzymatic synthesis of glycans and the mechanisms by which cellular glycans are regulated.