UFC 324 features Justin Gaethje vs Paddy Pimblett and Amanda Nunes vs Kayla Harrison in a stacked Las Vegas fight card.

Also on the main card is a women's flyweight matchup between former UFC titleholders Alexa Grasso and Rose Namajunas. Grasso (16-5-1 MMA, 8-5-1 UFC) will aim to return to the win

Gaethje vs. Pimblett is just the tip of the iceberg as Amanda Nunes is set to come out of retirement to take on champion Kayla Harrison

With all nine of his victories in the UFC having come by decision, the UFC made an executive one of its own. They went with Lopes, who, to his credit, has fought seven times since that debut loss to Evloev. Lopes beats Evloev in the realm of staying busy, even if he didn’t beat him in a literal fight.

Gaethje and Pimblett will be vying for the opportunity to face UFC lightweight champion Ilia Topuria, as the interim title will create a definitive No. 1 contender. The two of them recently became entangled when Pimblett had some sharp words for Gaethje's claim that "They owe me a championship fight."

In the co-main event, UFC women’s bantamweight champion Kayla Harrison (19-1-0) puts her title on the line against UFC Hall of Famer and former two-division champion Amanda Nunes (23-5-0).

UFC 322 brings a spectacular fight card, as Jack Della Maddalena looks to defend his title belt against Islam Makhachev.

The stage is set for UFC 322, headlined by the welterweight title bout between Jack Della Maddalena vs. Islam Makhachev, on Saturday, Nov. 15, 2025 (11/15/25) at Madison Square Garden in New York City.

Date, time, location and how to watch or stream the event with a Jack Della Maddalena vs. Islam Makhachev main event