The San Francisco 49ers dropped to 5-5 on the season after a 20-17 Week 10 loss to the Seattle Seahawks at Levi's Stadium in ...

Marching 80 yards in the closing moments, Geno Smith scrambled his way to the end zone to finally lead the Seahawks to a defeat of the 49ers.

San Francisco 49ers star running back Christian McCaffrey wasn't satisfied with his performance during a 20-17 loss to the ...

The Seattle Seahawks finally snapped their frustrating and painful losing streak to the San Francisco 49ers with a ...

Another devastating loss for the 49ers who drop to 5-5 on the season. This loss by the Seahawks is a reality check for the ...

The San Francisco 49ers needed a win Sunday at Levi’s Stadium against the Seattle Seahawks. Instead, they turned in a dud ...

Seahawks cornerback Devon Witherspoon deflected a Brock Purdy pass intended for Christian McCaffrey and it get intercepted by defensive lineman Johnathan Hankins for his first career pick.

The 34-year-old quarterback runs and throws Seattle to its 1st win over San Francisco in 7 tries, back into NFC West race.

Just last weekend Christian McCaffrey made his triumphant return to the San Francisco 49ers as they took down the Tampa Bay ...

NFC West foes battle it out on Sunday as the Seattle Seahawks take on the San Francisco 49ers in a pivotal matchup for ...

To say that this has been a disappointing season for the San Francisco 49ers would be an understatement. The team made it to ...

Want to watch Seattle play San Francisco? Here's everything you need to stream Sunday's 4:05 p.m. ET game on Fox.