Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Long-Term Efficacy and Tolerability of Aficamten in Patients with Non-Obstructive HCM Pre-Specified Analysis of Supplemental Endpoints from MAPLE-HCM Shows Aficamten Improves Measures of Submaximal ...

Stanford researchers reveal that Arctic diatoms are not frozen in place but actively moving in ice, reshaping our view of polar ecosystems.

Cytokinetics’ aficamten is a myosin inhibitor that reduces the interaction between actin and myosin to prevent muscle hypercontractility. Image Credit: Michael Vi / Shutterstock.com. Cytokinetics’ ...

Department of Physics, Graduate School of Science, University of Tokyo, Bunkyo, Japan In recent years, significant advances have been made in various fields related to the study of myosin, including ...

Skeletal muscles are voluntary muscles that can be consciously controlled, such as the muscles of your neck, arms, and legs. It makes up 30% to 40% of human body weight in a healthy person. The ...

The helper protein UNC45 ensures muscle health by managing the quality of myosin proteins. It removes defective ones and organizes functional ones, helping muscles work efficiently and preventing ...

The world's strongest lifters on record won acclaim for hoisting thousands of pounds into the air at one time. Could they ever go heavier? When you purchase through links on our site, we may earn an ...

Various heterozygous cytoskeletal γ-actin mutations have been shown to cause Baraitser–Winter cerebrofrontofacial syndrome, non-syndromic hearing loss, or isolated eye coloboma. Here, we report the ...