Three decades ago, in a lab at The Rockefeller University, New York City, Jeffrey Friedman, MD, PhD, observed a paradox that would forever change our understanding of obesity. His subjects, a rare ...
SOME PETS WERE RESCUED FROM HOMES. ALL NEW AT FIVE. AND FOR YOUR HEALTH, THE MEDICAL RESEARCHERS AT THE UNIVERSITY OF PITTSBURGH ARE AT IT AGAIN. THEY PUBLISHED RESEARCH LAST WEEK FOCUSING ON A WAY TO ...
A team of scientists has uncovered a critical mechanism that could pave the way for safer and more effective obesity treatments. The findings, published in Nature Communications, shed light on how ...
The leptin gene occurs in all mammals and was first discovered in mice. This gene produces a protein/hormone created by fat cells. The hormone signals the brain to regulate hunger and body weight. In ...
Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic ...
How do mammals manage to eat in situations that cause anxiety, step into exposed spaces, or slow down when anxiety drives them to keep moving? A new study pinpoints a leptin-sensitive circuit in the ...
For more than a hundred years, insulin has been the key to controlling type 1 diabetes. It has saved lives by preventing diabetic ketoacidosis (DKA), a life-threatening condition that happens when the ...
More than a decade ago, researchers found that an acute complication of type 1 diabetes, diabetic ketoacidosis (DKA), can be resolved with the hormone leptin, even in the absence of insulin. An ...
Obesity is often a combination of genetic and lifestyle factors. Genetics can influence metabolic pathways, appetite control, and energy storage. Leptin resistance can lead to increased appetite and ...