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The three best characterized Wnt signaling pathways are the canonical Wnt pathway, the noncanonical planar cell polarity pathway, and the noncanonical Wnt/calcium pathway.

This review offers an in-depth analysis of the Wnt pathway, detailing its signal transduction mechanisms and principal components. Furthermore, the complex network of interactions …

Wnt proteins are highly conserved in evolution and are active in every branch of the animal kingdom. Wnt signaling is often implicated in stem cell control, as a proliferative and self …

Jan 3, 2022 · In this article, we comprehensively review the Wnt/β-catenin pathway from the above five aspects in combination with the latest research.

Jun 18, 2025 · Explore the Wnt/β-catenin signaling pathway, understand its components, regulation, and therapeutic potential in disease.

Jun 16, 2025 · Wnt refers to a family of secreted proteins that facilitate communication between cells in virtually all animal species. The name “Wnt” combines “Wingless,” a gene from the fruit …

Wnts are extracellular secreted glycol proteins, consisted of a family of 19 human proteins that represent the complex nature of the regulatory structure and physiological efficiency of signaling.

Jul 28, 2025 · Wnt signaling is a fundamental communication system within the body, regulating how cells interact and behave. This intricate network of proteins and pathways guides …

Wnt genes can be expressed in many different cell types; their expression is not restricted to dedicated cells. There is control over the secretion and processing of the Wnt protein.